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James J Vredenburgh Selected Research

Vomiting

1/2017A Phase II single-arm trial of palonosetron for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in malignant glioma patients receiving multidose irinotecan in combination with bevacizumab.
10/2016Phase II study to evaluate the safety and efficacy of intravenous palonosetron (PAL) in primary malignant glioma (MG) patients receiving standard radiotherapy (RT) and concomitant temozolomide (TMZ).
3/2007Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting.

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James J Vredenburgh Research Topics

Disease

40Neoplasms (Cancer)
01/2020 - 01/2002
39Glioblastoma (Glioblastoma Multiforme)
01/2020 - 01/2004
36Glioma (Gliomas)
01/2017 - 01/2006
10Breast Neoplasms (Breast Cancer)
02/2006 - 01/2002
6Brain Neoplasms (Brain Tumor)
02/2012 - 01/2006
4Diarrhea
07/2012 - 01/2004
4Astrocytoma (Pilocytic Astrocytoma)
10/2011 - 01/2006
4Infections
01/2010 - 07/2003
3Meningioma (Meningiomas)
01/2019 - 01/2012
3Nausea
01/2017 - 03/2007
3Vomiting
01/2017 - 03/2007
3Fatigue
07/2012 - 12/2010
3Hemorrhage
01/2012 - 10/2009
3Lymphopenia (Lymphocytopenia)
01/2012 - 03/2011
3Hypoxia (Hypoxemia)
04/2011 - 01/2008
2Lymphoma (Lymphomas)
08/2013 - 06/2004
2Hypersensitivity (Allergy)
03/2011 - 11/2010
2Central Nervous System Neoplasms
02/2009 - 07/2007
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/2003 - 02/2003
1Smoldering Multiple Myeloma
11/2022
1Small Cell Carcinoma
10/2016
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2016
1Disease Progression
10/2015
1Tetanus
03/2015
1Diphtheria
03/2015
1Thrombocytopenia (Thrombopenia)
03/2012
1Pancreatitis
03/2012

Drug/Important Bio-Agent (IBA)

29Bevacizumab (Avastin)FDA Link
01/2020 - 02/2007
21Temozolomide (Temodar)FDA LinkGeneric
10/2016 - 04/2007
16Irinotecan (Camptosar)FDA LinkGeneric
01/2017 - 02/2007
12Monoclonal AntibodiesIBA
08/2012 - 05/2002
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2012 - 01/2008
9ErbB Receptors (EGF Receptor)IBA
07/2012 - 01/2004
8Carmustine (FIVB)FDA Link
08/2009 - 01/2002
7Cisplatin (Platino)FDA LinkGeneric
10/2016 - 01/2002
7Tyrosine Kinase InhibitorsIBA
07/2012 - 01/2004
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
02/2006 - 01/2002
6Imatinib Mesylate (Gleevec)FDA Link
10/2012 - 12/2005
5epidermal growth factor receptor VIIIIBA
01/2020 - 01/2010
5VaccinesIBA
01/2020 - 05/2008
5Hydroxyurea (Hydrea)FDA LinkGeneric
10/2012 - 12/2005
4Erlotinib Hydrochloride (CP 358,774)FDA Link
07/2012 - 01/2010
4EnzymesIBA
10/2010 - 02/2006
4O(6)-benzylguanineIBA
10/2009 - 02/2009
3AntiemeticsIBA
01/2017 - 03/2007
3Etoposide (VP 16)FDA LinkGeneric
10/2016 - 03/2003
3Alkylating AgentsIBA
08/2013 - 03/2002
3Peptides (Polypeptides)IBA
01/2012 - 05/2008
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
12/2011 - 05/2009
3TOR Serine-Threonine KinasesIBA
10/2011 - 02/2006
3Adrenal Cortex Hormones (Corticosteroids)IBA
01/2011 - 08/2008
3Phosphotransferases (Kinase)IBA
04/2010 - 07/2007
2EverolimusFDA Link
01/2019 - 10/2011
2Ondansetron (Zofran)FDA LinkGeneric
01/2017 - 03/2007
2Palonosetron (Aloxi)FDA Link
01/2017 - 10/2016
2AntigensIBA
03/2015 - 08/2002
2Proteins (Proteins, Gene)FDA Link
07/2012 - 10/2011
2Angiogenesis InhibitorsIBA
06/2012 - 04/2011
2Carboplatin (JM8)FDA LinkGeneric
03/2012 - 12/2011
2CytokinesIBA
01/2012 - 01/2002
2Anticonvulsants (Antiepileptic Drugs)IBA
10/2010 - 02/2006
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
04/2010 - 06/2008
2Sirolimus (Rapamycin)FDA Link
01/2010 - 02/2006
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2010 - 02/2006
2DNA (Deoxyribonucleic Acid)IBA
02/2009 - 05/2008
2laromustine (VNP40101M)IBA
07/2007 - 01/2007
2Adenosine Triphosphate (ATP)IBA
05/2007 - 12/2005
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
05/2007 - 12/2005
2Gefitinib (Iressa)FDA Link
02/2006 - 01/2004
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
04/2005 - 04/2002
1Biomarkers (Surrogate Marker)IBA
11/2022
1rindopepimutIBA
01/2020
1Epidermal Growth Factor (EGF)IBA
01/2020
1keyhole-limpet hemocyanin (keyhole limpet hemocyanin)IBA
01/2020
1Serotonin (5 Hydroxytryptamine)IBA
01/2017
1romidepsin (FK228)FDA Link
10/2016
1Topotecan (Hycamtin)FDA LinkGeneric
10/2016
1PlatinumIBA
10/2015
1cytomegalovirus matrix protein 65kDaIBA
03/2015
1RNA (Ribonucleic Acid)IBA
03/2015
1Viral ProteinsIBA
03/2015
1Tetanus Toxoid (Vaccine, Tetanus)FDA Link
03/2015
1ToxoidsIBA
03/2015
1MethyltransferasesIBA
08/2013
1Dasatinib (BMS 354825)FDA Link
07/2012
1src-Family KinasesIBA
07/2012
1BenzodiazepinesIBA
02/2012
1Phenytoin (Dilantin)FDA LinkGeneric
02/2012
1Pregabalin (Lyrica)FDA Link
02/2012
1Prostaglandins BIBA
02/2012

Therapy/Procedure

31Therapeutics
07/2015 - 06/2002
27Drug Therapy (Chemotherapy)
01/2017 - 01/2002
14Radiotherapy
10/2016 - 06/2002
5Stem Cell Transplantation
08/2004 - 01/2002
4Immunotherapy
11/2022 - 05/2008
4Salvage Therapy
03/2012 - 02/2007
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
02/2006 - 07/2003
2Transplantation
07/2003 - 04/2002
1Drug Tapering
04/2013
1Computer-Assisted Surgery (Image Guided Surgery)
06/2012